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. 1990 May;9(5):358-60.
doi: 10.1007/BF01973746.

Activity of gamma interferon in combination with pyrimethamine or clindamycin in treatment of murine toxoplasmosis

D Israelski  1 , J Remington
Affiliations

Activity of gamma interferon in combination with pyrimethamine or clindamycin in treatment of murine toxoplasmosis

D Israelski et al. Eur J Clin Microbiol Infect Dis. 1990 May.

Abstract

The activity of recombinant gamma interferon (rIFN-gamma) in combination with either pyrimethamine or clindamycin was examined in a murine model of acute toxoplasmosis. Mice received either pyrimethamine or clindamycin alone or in combination with rIFN-gamma. Significantly increased survival and/or time to death was observed in animals treated with pyrimethamine or clindamycin in combination with rIFN-gamma compared to those that received treatment with any of the agents alone.

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