YAP tips the balance

Comment

Mhairi Skinner. Nat Rev Cancer. 2010 Dec.

. 2010 Dec;10(12):811.

doi: 10.1038/nrc2973.

No abstract available

Comment on

The Hippo signaling pathway restricts the oncogenic potential of an intestinal regeneration program.
Cai J, Zhang N, Zheng Y, de Wilde RF, Maitra A, Pan D. Cai J, et al. Genes Dev. 2010 Nov 1;24(21):2383-8. doi: 10.1101/gad.1978810. Genes Dev. 2010. PMID: 21041407 Free PMC article.
The Lats2 tumor suppressor augments p53-mediated apoptosis by promoting the nuclear proapoptotic function of ASPP1.
Aylon Y, Ofir-Rosenfeld Y, Yabuta N, Lapi E, Nojima H, Lu X, Oren M. Aylon Y, et al. Genes Dev. 2010 Nov 1;24(21):2420-9. doi: 10.1101/gad.1954410. Genes Dev. 2010. PMID: 21041410 Free PMC article.
Cytoplasmic ASPP1 inhibits apoptosis through the control of YAP.
Vigneron AM, Ludwig RL, Vousden KH. Vigneron AM, et al. Genes Dev. 2010 Nov 1;24(21):2430-9. doi: 10.1101/gad.1954310. Genes Dev. 2010. PMID: 21041411 Free PMC article.