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Comment
. 2010 Dec 14;18(6):543-5.
doi: 10.1016/j.ccr.2010.11.028.

The Ids have it

Lincoln A Edwards  1 , Howard A Fine
Affiliations
Comment

The Ids have it

Lincoln A Edwards et al. Cancer Cell. .

Abstract

In this issue of Cancer Cell, Anido et al. demonstrate that Id1 is the likely arbiter of divergent transforming growth factor-β (TGF-β) signaling in glioma-initiating cells (GICs) from different tumors. These findings hold both the promise and potential peril of therapeutic targeting of the TGF-β pathway.

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