Viral-derived Serp-1 as an adjunctive therapy for percutaneous coronary intervention: another not ready for prime time player?
- PMID: 21156927
- PMCID: PMC3047481
- DOI: 10.1161/CIRCINTERVENTIONS.110.959684
Viral-derived Serp-1 as an adjunctive therapy for percutaneous coronary intervention: another not ready for prime time player?
Comment on
-
A randomized controlled, phase 2 trial of the viral serpin Serp-1 in patients with acute coronary syndromes undergoing percutaneous coronary intervention.Circ Cardiovasc Interv. 2010 Dec;3(6):543-8. doi: 10.1161/CIRCINTERVENTIONS.110.953885. Epub 2010 Nov 9. Circ Cardiovasc Interv. 2010. PMID: 21062996 Clinical Trial.
Similar articles
-
A randomized controlled, phase 2 trial of the viral serpin Serp-1 in patients with acute coronary syndromes undergoing percutaneous coronary intervention.Circ Cardiovasc Interv. 2010 Dec;3(6):543-8. doi: 10.1161/CIRCINTERVENTIONS.110.953885. Epub 2010 Nov 9. Circ Cardiovasc Interv. 2010. PMID: 21062996 Clinical Trial.
-
Viral serine proteinase inhibitor (SERP-1) effectively decreases the incidence of graft vasculopathy in heterotopic heart allografts.Transplantation. 2001 Aug 15;72(3):364-8. doi: 10.1097/00007890-200108150-00003. Transplantation. 2001. PMID: 11502962
-
Virus-encoded serine proteinase inhibitor SERP-1 inhibits atherosclerotic plaque development after balloon angioplasty.Circulation. 1996 Dec 1;94(11):2890-900. doi: 10.1161/01.cir.94.11.2890. Circulation. 1996. PMID: 8941118
-
The serpin saga; development of a new class of virus derived anti-inflammatory protein immunotherapeutics.Adv Exp Med Biol. 2009;666:132-56. doi: 10.1007/978-1-4419-1601-3_11. Adv Exp Med Biol. 2009. PMID: 20054981 Review.
-
Serpins for diagnosis and therapy in cancer.Cardiovasc Hematol Disord Drug Targets. 2013 Aug;13(2):123-32. doi: 10.2174/1871529x11313020005. Cardiovasc Hematol Disord Drug Targets. 2013. PMID: 23988000 Review.
References
-
- Bryson B. In A Sunburned Country. Canada: Random House; 2000.
-
- Lomas DA, Evans DL, Upton C, McFadden G, Carrell RW. Inhibition of plasmin, urokinase, tissue plasminogen activator, and C1S by a myxoma virus serine proteinase inhibitor. J Biol Chem. 1993;268:516–521. - PubMed
-
- Nash P, Whitty A, Handwerker J, Macen J, McFadden G. Inhibitory specificity of the anti-inflammatory myxoma virus serpin, SERP-1. J Biol Chem. 1998;273:20982–20991. - PubMed
-
- Silverman GA, Bird PI, Carrell RW, Church FC, Coughlin PB, Gettins PG, Irving JA, Lomas DA, Luke CJ, Moyer RW, Pemberton PA, Remold-O’Donnell E, Salvesen GS, Travis J, Whisstock JC. The serpins are an expanding superfamily of structurally similar but functionally diverse proteins. Evolution, mechanism of inhibition, novel functions, and a revised nomenclature. J Biol Chem. 2001;276:33293–33296. - PubMed
-
- Lucas A, Liu L, Dai E, Bot I, Viswanathan K, Munuswamy-Ramunujam G, Davids JA, Bartee MY, Richardson J, Christov A, Wang H, Macaulay C, Poznansky M, Zhong R, Miller L, Biessen E, Richardson M, Sullivan C, Moyer R, Hatton M, Lomas DA, McFadden G. The serpin saga; development of a new class of virus derived anti-inflammatory protein immunotherapeutics. Adv Exp Med Biol. 2009;666:132–156. - PubMed
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources