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. 2010 Oct;27(4):118-22.
doi: 10.4103/0970-9371.73293.

Study of cytomorphology of solid pseudopapillary tumor of pancreas and its differential diagnosis

Neelam Mehta  1 , Lopa Modi, Trupti Patel, Manoj Shah
Affiliations

Study of cytomorphology of solid pseudopapillary tumor of pancreas and its differential diagnosis

Neelam Mehta et al. J Cytol. 2010 Oct.

Abstract

Background: Solid pseudopapillary tumor is a rare pancreatic neoplasm with uncertain to low malignant potential. This is an uncommon neoplasm with many pseudonyms, occurring predominantly in young woman under the age of thirty years.

Aims: To study the cytomorphological features of six cases of solid and pseudopapillary epithelial neoplasm of pancreas diagnosed on fine needle aspiration cytology (FNAC) in years 2005 to 2007 and its cyto-histological correlation.

Materials and methods: Image-guided FNAs was done in these six patients preoperatively. Alcohol-fixed smears were stained with Papanicolaou stain, cytomorphological findings were evaluated and diagnosis was made. Diagnosis was later confirmed by histology in all cases.

Results: All six cases show characteristic cytological features such as hypercellular smears with presence of abundant delicate papillary fragments, dyscohesive cells, monomorphic tumor cells with delicate folded nuclear membranes, and foamy macrophages in the background.

Conclusions: Preoperative correct diagnosis of solid pseudopapillary tumor of pancreas is possible on FNAC and by doing so it helps in management of this surgically curable neoplasm.

Keywords: Solid pseudopapillary tumor; pancreas; aspiration cytology; ultrasound guided.

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Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
FNAC smear from case of SPT showing tumor cells arranged in papillary pattern and discrete cells (Pap, ×100)
Figure 2
Figure 2
FNAC smear from a case of SPT showing discrete cell (Pap, ×200)
See this image and copyright information in PMC

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