Subcutaneous sarcoidosis with plantar involvement

Abstract

Sarcoidosis is a multisystem granulomatous disorder of an unknown etiology. Subcutaneous sarcoidosis is a rare manifestation of sarcoidosis, and plantar involvement is extremely rare and there is only one such case report in the medical literature. Herein we present an interesting case of a patient who was diagnosed as having subcutaneous sarcoidosis at a plantar localization because plantar involvement is extremely rare and also because of the successful outcome after performing intralesional corticosteroid therapy.

Keywords: Intralesional corticosteroid; Plantar; Subcutaneous sarcoidosis.

Fig. 1

Subcutaneous nodule on the plantar surface of the patient's foot.

Fig. 2

Histopathologic examination shows well-circumbscribed non-necrotizing granulomas consisting of epithelioid histiocytes and Langhans giant cells in a fibrous stroma (A: H&E, ×100, B: H&E, ×200).

Fig. 3

The hyperkeratotic layer of the sole and the granuloma adjacent to the epidermis (H&E, ×100).

Fig. 4

Bilateral hilar enlargement and reticulonodular infiltration on the chest radiograph.

Fig. 5

Complete improvement of the subcutaneous lesion after intralesional corticosteroid injection.