Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Randomized Controlled Trial
. 2011 Jul;15(5):885-96.
doi: 10.1007/s10461-010-9865-y.

Group motivational interviewing to promote adherence to antiretroviral medications and risk reduction behaviors in HIV infected women

Marcia McDonnell Holstad  1 , Colleen DiIorio, Mary E Kelley, Kenneth Resnicow, Sanjay Sharma
Affiliations
Randomized Controlled Trial

Group motivational interviewing to promote adherence to antiretroviral medications and risk reduction behaviors in HIV infected women

Marcia McDonnell Holstad et al. AIDS Behav. 2011 Jul.

Abstract

We present the results of a clinical trial that tested the efficacy of using motivational interviewing (MI) in a group format to promote adherence to antiretroviral medications and risk reduction behaviors (RRB) in 203 predominately African American HIV infected women. It was compared to a group health promotion program. Participants were followed for 9 months. Adherence was measured by MEMS(®); and RRB by self-report. Controlling for recruitment site and years on ART, no significant group by time effects were observed. Attendance (≥7/8 sessions) modified the effects. Higher MI attendees had better adherence at all follow-ups, a borderline significant group by time effect (p = 0.1) for % Doses Taken on Schedule, a significantly larger proportion who reported abstinence at 2 weeks, 6, and 9 months, and always used protection during sex at 6 and 9 months. Though not conclusive, the findings offer some support for using MI in a group format to promote adherence and some risk reduction behaviors when adequate attendance is maintained.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Flowchart of KHARMA project recruitment, allocation, and retention
Fig. 2
Fig. 2
Mean percentage of doses taken by attendance for the MI and HPP groups
Fig. 3
Fig. 3
Mean percentage of doses taken on schedule by attendance for the MI and HPP groups
Fig. 4
Fig. 4
Mean CD4 percents for MI and HPP groups
Fig. 5
Fig. 5
Proportion of those with an undectable viral load (log) for MI and HPP groups
See this image and copyright information in PMC

References

    1. CDC Effect of antiretroviral therapy on risk of sexual transmission of HIV infection and superinfection: centers for disease control and prevention. 2009 September;
    1. CDC Recommendations for use of antiretroviral drugs in pregnant HIV-infected women for maternal health and interventions to reduce perinatal HIV transmission in the United States. 2009 cited 2009 October 18. - PubMed
    1. Remien RH, Exner T, Kertzner RM, Ehrhardt AA, Rotheram-Borus MJ, Johnson MO, et al. Depressive symptomatology among HIV-positive women in the era of HAART: a stress and coping model. Am J Community Psychol. 2006;38(3–4):275–85. - PubMed
    1. Wilson TE, Barron Y, Cohen M, Richardson J, Greenblatt R, Sacks HS, et al. Adherence to antiretroviral therapy and its association with sexual behavior in a national sample of women with human immunodeficiency virus. Clin Infect Dis. 2002;34(4):529–34. - PubMed
    1. Kalichman S, Rompa D. HIV treatment adherence and unprotected sex practices in people receiving antiretroviral therapy. Sex Transm Infect. 2003;79:59–61. - PMC - PubMed

Publication types

Substances