Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2010 Dec;42(10):3951-3.
doi: 10.1016/j.transproceed.2010.10.004.

Impact of cold ischemia on renal transplant outcomes following donation after cardiac death

J K Pine  1 , P J Goldsmith, D M Ridgway, R Baker, C G Newstead, S G Pollard, K V Menon, N Ahmad, M Attia
Affiliations

Impact of cold ischemia on renal transplant outcomes following donation after cardiac death

J K Pine et al. Transplant Proc. 2010 Dec.

Abstract

Donation after cardiac death (DCD) provides grafts in renal transplantation but is associated with increased early graft dysfunction. Cold ischemia time (CIT) is a factor that is thought to affect outcomes in renal transplantation. We sought to assess the impact of the length of CIT among our DCD cohort of renal transplants performed between April 2002 and December 2009. Since the median CIT was 15.5 hours, we formed two groups CIT < 15.5 (n = 100) and CIT > 15.5 hr (n = 98). We demonstrated an increased incidence of DGF among the extended CIT group, but the long outcomes and the mean graft function were otherwise comparable. In conclusion, CIT affects early graft function; every effort should be made to minimize it in renal transplantation using DCD kidneys.

PubMed Disclaimer

LinkOut - more resources