Oxidative kinetic self-sorting of a dynamic imine library
- PMID: 21171598
- DOI: 10.1021/ja109754t
Oxidative kinetic self-sorting of a dynamic imine library
Abstract
Dynamic libraries of [n × n] imine components spontaneously simplify during a slow oxidation reaction to produce only n discrete products. The selectivity of this self-sorting process is a consequence of different oxidation rates for various imines, while the dynamic nature of the library enables self-sorting to proceed with high efficiency.
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