The reactive serine residue of epidermolytic toxin A
- PMID: 2117445
- PMCID: PMC1131611
- DOI: 10.1042/bj2690535
The reactive serine residue of epidermolytic toxin A
Abstract
Comparison of amino acid sequence data suggested that there may be a functional relationship between the staphylococcal epidermolytic toxins and V8 proteinase. The hypothesis was tested by treating epidermolytic toxin with di-isopropyl phosphorofluoridate, which bound specifically at serine-195, the homologue of the active-site serine residue of V8 proteinase.
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