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. 2011 Feb;77(4):1516-9.
doi: 10.1128/AEM.02176-10. Epub 2010 Dec 23.

Influence of two-component signal transduction systems of Lactobacillus casei BL23 on tolerance to stress conditions

Cristina Alcántara  1 , Ainhoa Revilla-Guarinos, Manuel Zúñiga
Affiliations

Influence of two-component signal transduction systems of Lactobacillus casei BL23 on tolerance to stress conditions

Cristina Alcántara et al. Appl Environ Microbiol. 2011 Feb.

Abstract

Lactobacillus casei BL23 carries 17 two-component signal transduction systems. Insertional mutations were introduced into each gene encoding the cognate response regulators, and their effects on growth under different conditions were assayed. Inactivation of systems TC01, TC06, and TC12 (LCABL_02080-LCABL_02090, LCABL_12050-LCABL_12060, and LCABL_19600-LCABL_19610, respectively) led to major growth defects under the conditions assayed.

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Figures

FIG. 1.
FIG. 1.
Growth of L. casei BL23 and TCS-defective mutants under different conditions (only strains that displayed significant differences with strain BL23 are shown). Error bars indicate standard deviations (at least three replicates).
See this image and copyright information in PMC

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