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. 2011 Feb 7;47(5):1446-8.
doi: 10.1039/c0cc04564k. Epub 2010 Dec 24.

Gold catalyzes the Sonogashira coupling reaction without the requirement of palladium impurities

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Gold catalyzes the Sonogashira coupling reaction without the requirement of palladium impurities

Avelino Corma et al. Chem Commun (Camb). .

Abstract

By a combination of kinetic and theoretical studies it is concluded that gold is intrinsically active to perform the Sonogashira coupling reaction between phenylacetylene and iodobenzene. The presence of Pd impurities is not mandatory for catalyst activity.

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