Gold catalyzes the Sonogashira coupling reaction without the requirement of palladium impurities
- PMID: 21183985
- DOI: 10.1039/c0cc04564k
Gold catalyzes the Sonogashira coupling reaction without the requirement of palladium impurities
Abstract
By a combination of kinetic and theoretical studies it is concluded that gold is intrinsically active to perform the Sonogashira coupling reaction between phenylacetylene and iodobenzene. The presence of Pd impurities is not mandatory for catalyst activity.
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