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Review
. 2011 Feb;91(1):249-66.
doi: 10.1016/j.suc.2010.10.012.

Positron emission tomography for benign and malignant disease

Anthony Visioni  1 , Julian Kim
Affiliations
Review

Positron emission tomography for benign and malignant disease

Anthony Visioni et al. Surg Clin North Am. 2011 Feb.

Abstract

Functional imaging using radiolabeled probes that specifically bind and accumulate in target tissues has improved the sensitivity and specificity of conventional imaging. Fluorodeoxyglucose (FDG)-positron emission tomography (PET) has shown improved diagnostic accuracy in differentiating benign from malignant lesions in the setting of solitary pulmonary nodules. FDG-PET has become useful in preoperative staging of patients with lung cancer, and is being tested with many other malignancies for its ability to change patient management. This article provides an overview of the current status of FDG-PET and presents the challenges of moving toward routine use.

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Figures

Figure 1
Figure 1. PET-CT Images in a patient with known left superficial inguinal lymph node metastasis
A. Whole body PET CT demonstrating hypermetabolic left inguinal lymph node (arrow) consistent with metastatic melanoma. B. Coronal view of PET-CT demonstrating hypermetabolic left inguinal lymph node (arrow) and showing anatomic relationship of surrounding muscles and blood vessels. C. Coronal view of PET-CT demonstrating a deep iliac lymph node (arrow) suspicious for metastasis in the same patient. The large hypermetabolic focus in the central pelvis is the urinary bladder. D. Coronal view of PET-CT demonstrating hypermetabolic focus within the right scapula (arrow) in the same patient. The detection of this bone lesion prompted a biopsy and ultimately altered the treatment plan of the patient.
Figure 1
Figure 1. PET-CT Images in a patient with known left superficial inguinal lymph node metastasis
A. Whole body PET CT demonstrating hypermetabolic left inguinal lymph node (arrow) consistent with metastatic melanoma. B. Coronal view of PET-CT demonstrating hypermetabolic left inguinal lymph node (arrow) and showing anatomic relationship of surrounding muscles and blood vessels. C. Coronal view of PET-CT demonstrating a deep iliac lymph node (arrow) suspicious for metastasis in the same patient. The large hypermetabolic focus in the central pelvis is the urinary bladder. D. Coronal view of PET-CT demonstrating hypermetabolic focus within the right scapula (arrow) in the same patient. The detection of this bone lesion prompted a biopsy and ultimately altered the treatment plan of the patient.
See this image and copyright information in PMC

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