C. elegans star proteins, GLD-1 and ASD-2, regulate specific RNA targets to control development
- PMID: 21189689
- DOI: 10.1007/978-1-4419-7005-3_8
C. elegans star proteins, GLD-1 and ASD-2, regulate specific RNA targets to control development
Abstract
A comprehensive understanding of the C. elegans STAR proteins GLD-1 and ASD-2 is emerging from a combination of studies. Those employing genetic analysis reveal in vivo function, others involving biochemical approaches pursue the identification of mRNA targets through which these proteins act. Lastly, mechanistic studies provide the molecular pathway of target mRNA regulation.
Similar articles
-
The RNA-binding proteins PUF-5, PUF-6, and PUF-7 reveal multiple systems for maternal mRNA regulation during C. elegans oogenesis.Dev Biol. 2007 Mar 15;303(2):635-49. doi: 10.1016/j.ydbio.2006.12.004. Epub 2006 Dec 8. Dev Biol. 2007. PMID: 17234175
-
RNA target specificity of the STAR/GSG domain post-transcriptional regulatory protein GLD-1.Nat Struct Mol Biol. 2004 Jan;11(1):20-8. doi: 10.1038/nsmb706. Epub 2003 Dec 29. Nat Struct Mol Biol. 2004. PMID: 14718919
-
STAR-studded circuitry.Nat Struct Mol Biol. 2004 Jan;11(1):2-3. doi: 10.1038/nsmb0104-2. Nat Struct Mol Biol. 2004. PMID: 14718911 No abstract available.
-
Roles of microRNAs in the Caenorhabditis elegans nervous system.J Genet Genomics. 2013 Sep 20;40(9):445-52. doi: 10.1016/j.jgg.2013.07.002. Epub 2013 Aug 7. J Genet Genomics. 2013. PMID: 24053946 Review.
-
RNA-binding proteins.WormBook. 2006 Apr 18:1-13. doi: 10.1895/wormbook.1.79.1. WormBook. 2006. PMID: 18050487 Free PMC article. Review.
Cited by
-
Identification of proteins and miRNAs that specifically bind an mRNA in vivo.Nat Commun. 2019 Sep 16;10(1):4205. doi: 10.1038/s41467-019-12050-7. Nat Commun. 2019. PMID: 31527589 Free PMC article.
-
Stem cell proliferation versus meiotic fate decision in Caenorhabditis elegans.Adv Exp Med Biol. 2013;757:71-99. doi: 10.1007/978-1-4614-4015-4_4. Adv Exp Med Biol. 2013. PMID: 22872475 Free PMC article. Review.
-
In vivo and transcriptome-wide identification of RNA binding protein target sites.Mol Cell. 2011 Dec 9;44(5):828-40. doi: 10.1016/j.molcel.2011.11.009. Mol Cell. 2011. PMID: 22152485 Free PMC article.
-
Initiation of Meiotic Development Is Controlled by Three Post-transcriptional Pathways in Caenorhabditis elegans.Genetics. 2018 Aug;209(4):1197-1224. doi: 10.1534/genetics.118.300985. Epub 2018 Jun 25. Genetics. 2018. PMID: 29941619 Free PMC article.
-
Redundant mechanisms regulating the proliferation vs. differentiation balance in the C. elegans germline.Front Cell Dev Biol. 2022 Sep 2;10:960999. doi: 10.3389/fcell.2022.960999. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 36120589 Free PMC article. Review.
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources