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. 2010 May;53(5):629-33.
doi: 10.3345/kjp.2010.53.5.629. Epub 2010 May 31.

Update on pertussis and pertussis immunization

Jung Yun Hong  1
Affiliations

Update on pertussis and pertussis immunization

Jung Yun Hong. Korean J Pediatr. 2010 May.

Abstract

Pertussis is a highly contagious respiratory tract disease caused by Bordetella pertussis infection. The clinical manifestation of this infection can be severe enough to cause death. Although pertussis has been supposed to be a vaccine-preventable disease ever since the widespread vaccination of children against pertussis was started, since the 1990s, cases of pertussis and related fatalities are on the rise, especially in countries with high vaccination coverage. In Korea, there have been no deaths due to pertussis since 1990, and the vaccination rate continues to be approximately 94%. However, the number of pertussis cases reported to the Korea Center for Disease Control and Prevention has tended to increase in the 2000s, and in 2009, there was an obvious increase in the number of pertussis cases reported. This review aims to present the latest information about the pathogenesis, diagnosis, treatment, and prevention of pertussis.

Keywords: Outbreak; Pertussis; Vaccination.

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Figures

Fig. 1
Fig. 1
Number of cases of pertussis reported in Korea (1995-2009).
Fig. 2
Fig. 2
Manifestations and complications of pertussis. Abbreviations : DFA, direct fluorescent antibody; PCR, polymerase chain reaction. Adapted from Cherry JD, Brunell PA, Golden GS, et al. Report of the task force on pertussis and pertussis immunization-1988. Pediatrics 1988;81[Suppl]:939-84.)
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