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Comment
. 2011 Jan 5;13(1):7-8.
doi: 10.1016/j.cmet.2010.12.016.

FTO and obesity: the missing link

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FTO and obesity: the missing link

I Sadaf Farooqi. Cell Metab. .
Free article

Abstract

Genome-wide association studies revealed that variants within FTO (fat-mass- and obesity-associated) are strongly associated with obesity susceptibility. A recent study in Nature Genetics (Church et al., 2010) demonstrates that mice overexpressing fto exhibit a dose-dependent increase in body weight, confirming a role for FTO in the development of obesity.

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