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Case Reports
. 2010 Oct;51(10):1143-5.

Accidental salinomycin intoxication in calves

Arash Omidi  1 , Mohammad R Aslani, Ahmad R Movassaghi, Mehrdad Mohri, Mohammad Dadfar
Affiliations
Case Reports

Accidental salinomycin intoxication in calves

Arash Omidi et al. Can Vet J. 2010 Oct.

Abstract
in English, French

Twenty-four 10- to 16-week-old calves in a dairy herd in Birjand, Iran, inadvertently received an excessive dose of salinomycin mixed with barley grain. There was 58% mortality within 10 d. The calves had high serum AST, LDH, and CK activities; histopathologic lesions in myocardium, liver, and kidneys; and clinical signs associated with acute and congestive heart failure.

Intoxication accidentelle à la salinomycine chez des veaux. Vingt-quatre veaux âgés de 10 à 16 semaines faisant partie d’un troupeau laitier de Birjand, en Iran, ont reçu par inadvertance une dose excessive de salinomycine mélangée avec du grain d’orge. Il s’est produit une mortalité de 58 % dans un délai de 10 jours. Les veaux présentaient des activités sériques SGOT, LDH et CK élevées, des lésions histopathologiques du myocarde, du foie et des reins et des signes cliniques associés à une insuffisance cardiaque congestive.

(Traduit par Isabelle Vallières)

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Figures

Figure 1
Figure 1
Tongue paralysis, facial edema, and sunken eyes in case of salinomycin poisoning.
Figure 2
Figure 2
Hepatocytes showing fatty change and single cell necrosis. Hematoxylin and eosin, X640.
Figure 3
Figure 3
Renal tubules showing coagulative necrosis of the convoluted tubules. Hematoxylin and eosin, X640.
Figure 4
Figure 4
Severe epicardial hemorrhage. Hematoxylin and eosin, X160.
Figure 5
Figure 5
Focal necrosis of cardiac muscle cells. Hematoxylin and eosin, X320.
See this image and copyright information in PMC

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