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Review
. 2011 Feb;44(1):86-98.
doi: 10.1111/j.1365-2184.2010.00736.x.

Adipose-derived stem cells for clinical applications: a review

Affiliations
Review

Adipose-derived stem cells for clinical applications: a review

A Wilson et al. Cell Prolif. 2011 Feb.

Abstract

The use of stem cells derived from adipose tissue as an autologous and self-replenishing source for a variety of differentiated cell phenotypes, provides a great deal of promise for reconstructive surgery. In this article, we review available literature encompassing methods of extraction of pluripotent adipose stem cells (ASCs) from lipoaspirate locations, their storage, options for culture, growth and differentiation, cryopreservation and its effect on stem cell survival and proliferation, and new technologies involving biomaterials and scaffolds. We will conclude by assessing potential avenues for developing this incredibly promising field.

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Figures

Figure 1
Figure 1
Anatomical regions most commonly associated with liposuction ( http://www.aestheticsurgery.ie/images/liposuction1.jpg ).
Figure 2
Figure 2
Technique of liposuction ( http://www.aestheticsurgery.ie/images/liposuction1.jpg ).
Figure 3
Figure 3
Procedure for extraction of ADSCs from aspirated adipose tissue [adapted from ( 73 )].
Figure 4
Figure 4
Alizarin Red staining of adipocytes/ASCs ( http://guldberglab.ibb.gatech.edu/images/04_hADSC_miner_wtext.jpg ).

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References

    1. Neuber F (1993) Fettransplantation. Bericht uber die Verhandlungen der Deutscht Gesellsch Chir. 22, 66.
    1. Peer L (1950) Loss of weight and volume in human fat grafts. Plast. Reconstr. Surg. 5, 217.
    1. Phulpin B, Gangloff P, Tran N, Bravetti P, Merlin JL, Dolivet G (2009) Rehabilitation of irradiated head and neck tissues by autologous fat transplantation. Plast. Reconstr. Surg. 123, 1187–1197. - PubMed
    1. Sinna R, Delay E, Garson S, Delaporte T, Toussoun G (2010) Breast fat grafting (lipomodelling) after extended latissimus dorsi flap breast reconstruction: a preliminary report of 200 consecutive cases. J. Plast. Reconstr. Aesthet. Surg. 63, 1769–1777. - PubMed
    1. Sterodimas A, Huanquipaco J, de Souza Filho S, Bornia FA, Pitanguy I (2009) Autologous fat transplantation for the treatment of Parry‐Romberg syndrome. J. Plast. Reconstr. Aesthet. Surg. 62, 424–426. - PubMed

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