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. 2011 Jan:127 Suppl 1:10S-20S.
doi: 10.1097/PRS.0b013e3181fbe2d8.

The role of stem cells in cutaneous wound healing: what do we really know?

Affiliations

The role of stem cells in cutaneous wound healing: what do we really know?

Sae Hee Ko et al. Plast Reconstr Surg. 2011 Jan.

Abstract

Wound repair is a complex process involving the orchestrated interaction of multiple growth factors, cytokines, chemokines, and cell types. Dysregulation of this process leads to problems such as excessive healing in the form of keloids and hypertrophic scars and chronic, nonhealing wounds. These issues have broad global implications. Stem cells offer enormous potential for enhancing tissue repair and regeneration following injury. The rapidly developing fields of stem cell biology and skin tissue engineering create translational opportunities for the development of novel stem cell-based wound-healing therapies.

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References

    1. Gurtner GC, Werner S, Barrandon Y, et al. Wound repair and regeneration. Nature 2008;453:314–321.
    1. Thomson JA, Itskovitz-Eldor J, Shapiro SS, et al. Embryonic stem cell lines derived from human blastocysts. Science 1998;282:1145–1147.
    1. Aberdam D. Derivation of keratinocyte progenitor cells and skin formation from embryonic stem cells. Int J Dev Biol. 2004;48:203–206.
    1. Cha J, Falanga V. Stem cells in cutaneous wound healing. Clin Dermatol. 2007;25:73–78.
    1. Pera MF, Hasegawa K. Simpler and safer cell reprogramming. Nat Biotechnol. 2008;26:59–60.