Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2007 Dec 6;64(Pt 1):o199-200.
doi: 10.1107/S1600536807063477.

(5S,6S,10R)-10-(2,4-Dichloro-phen-yl)-14-[(E)-(2,4-dichloro-phen-yl)methyl-idene]-3,9-diphenyl-12-[(R)-1-phenyl-ethyl]-1,4,7-trioxa-2,8,12-triaza-dispiro-[4.0.4.4]tetra-deca-2,8-diene

S Mahalakshmi, R Suresh Kumar, S Perumal, V Sivakumar, J Suresh

(5S,6S,10R)-10-(2,4-Dichloro-phen-yl)-14-[(E)-(2,4-dichloro-phen-yl)methyl-idene]-3,9-diphenyl-12-[(R)-1-phenyl-ethyl]-1,4,7-trioxa-2,8,12-triaza-dispiro-[4.0.4.4]tetra-deca-2,8-diene

S Mahalakshmi et al. Acta Crystallogr Sect E Struct Rep Online. .

Abstract

The asymmetric unit of the title compound, C(41)H(31)Cl(4)N(3)O(3), contains two independent mol-ecules with almost identical geometries. The piperidine ring adopts a chair conformation in both mol-ecules, and the dihydro-isoxazole rings adopt envelope conformations. The crystal structure is stabilized by C-H⋯N hydrogen bonds and C-H⋯π inter-actions.

PubMed Disclaimer

Figures

Fig. 1.
Fig. 1.
One of the two independent molecules (molecule A), showing the atom-numbering scheme. Displacement ellipsoids are drawn at the 25% probability level. H atoms have been omitted for clarity.
Fig. 2.
Fig. 2.
One of the two independent molecules (molecule B), showing the atom-numbering scheme. Displacement ellipsoids are drawn at the 25% probability level. H atoms have been omitted for clarity.
See this image and copyright information in PMC

References

    1. Curran, D. P. (1983). J. Am. Chem. Soc.105, 5826–5833.
    1. De Amici, M., De Micheli, M. & Misani, V. (1990). Tetrahedron, 46, 1975–1986.
    1. Diana, G. D., McKinlay, M. A., Brisson, C. J., Zalay, E. S., Miralles, J. V. & Salvador, U. J. (1985). J. Med. Chem.28, 748–752. - PubMed
    1. Enraf–Nonius (1994). CAD-4 EXPRESS Version 5.0. Enraf–Nonius, Delft, The Netherlands.
    1. Faulkner, J. (2001). Nat. Prod. Rep.18, 1–49. - PubMed

LinkOut - more resources