3-[(R)-3,3-Dichloro-2-hydroxy-prop-yl]-8-hydr-oxy-6-meth-oxy-1H-isochromen-1-one

Abstract

The title compound, C(13)H(12)Cl(2)O(5), is an isocoumarin compound which has been isolated from the ethyl acetate extract of the fermentation broth of actinomycete Streptomyces sp. (V(4)) from the South China Sea. There are intra- and inter-molecular hydrogen bonds and halogen bonds [Cl⋯Cl = 3.434 (2) Å; C-Cl⋯Cl = 121.6°]. The intermolecular O-H⋯O hydrogen bonds link mol-ecules into chains along the b axis.

Fig. 1.

View of the molecules in the asymmetric unit of (I), with anisotropic displacement parameters drawn at the 50% probability level.

Fig. 2.

A view of the hydrogen-bonded molecular chains (Dashed lines). The chains are aligned parallel to the crystallographic b axis. H atoms not involved in H-bonding have been omitted for clarity. Symmetry codes: (I) 1 - x,y - 1/2,-z; (II) 1 - x,1/2 + y,-z.

Fig. 3.

Supplementary figure.