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Review
. 2010 Oct;1(10):888-97.
doi: 10.1007/s13238-010-0113-z. Epub 2010 Nov 9.

Human catalase: looking for complete identity

Madhur M Goyal  1 , Anjan Basak
Affiliations
Review

Human catalase: looking for complete identity

Madhur M Goyal et al. Protein Cell. 2010 Oct.

Abstract

Catalases are well studied enzymes that play critical roles in protecting cells against the toxic effects of hydrogen peroxide. The ubiquity of the enzyme and the availability of substrates made heme catalases the focus of many biochemical and molecular biology studies over 100 years. In human, this has been implicated in various physiological and pathological conditions. Advancement in proteomics revealed many of novel and previously unknown features of this mysterious enzyme, but some functional aspects are yet to be explained. Along with discussion on future research area, this mini-review compile the information available on the structure, function and mechanism of action of human catalase.

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