Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2010 Sep;16(3):159-63.
doi: 10.4103/0971-6866.73412.

Congenital malformations at birth in Central India: A rural medical college hospital based data

Affiliations

Congenital malformations at birth in Central India: A rural medical college hospital based data

Amar Taksande et al. Indian J Hum Genet. 2010 Sep.

Abstract

Objective: To study the incidence of congenital anomalies and the associated risk factors in Department of Pediatrics at Mahatma Gandhi Institute of Medical Sciences, Sevagram, Wardha, a rural medical college hospital in central Maharashtra.

Materials and methods: All the intramural deliveries between 1 January 2005 and 31 July 2007 comprised 9386 births and their 9324 mothers (62 mothers gave birth to twin babies). The newborns were examined and assessed systematically for the presence of congenital anomalies, system wise distribution of anomalies and risk factors attributable.

Results: Out of the total 9386 deliveries, 9194 were live births and 192 were stillbirths. The total number of babies with congenital malformations was 179 (1.91%). Out of the 9262 singleton births, 177 (1.05%) were malformed, whereas 2 of the 62 pairs of twins had birth defects. Nine of the 179 malformed babies (5.02%) were still born. Prematurity, increased maternal age, increasing birth order and low birth weight were found to have a higher risk of congenital anomalies. Cardiovascular malformations were most common in live births, followed by musculoskeletal and genitourinary anomalies.

Conclusion: Congenital anomalies are a major cause of stillbirths and infant mortality. Evaluation of cardiovascular system to rule out congenital heart disease in high-risk mothers' babies is the important factor to be considered.

Keywords: Cardiovascular; congenital; infant; malformation; musculoskeletal.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest: None declared

References

    1. Patel ZM, Adhia RA. Birth defects surveillance study. Indian J Pediatr. 2005;72:489–91. - PubMed
    1. Bhat BV, Ravikumara M. Perinatal mortality in India-Need for introspection. Indian J Matern Child Health. 1996;7:31–3.
    1. Agarwal SS, Singh U, Singh PS, Singh SS, Das V, Sharma A, et al. Prevalence and spectrum of congenital malformations in a prospective study at a teaching hospital. Indian J Med Res. 1991;94:413–9. - PubMed
    1. Chaturvedi P, Banerjee KS. Spectrum of congenital malformations in newborns from rural Maharashtra. Indian J Pediatr. 1989;56:501–7. - PubMed
    1. Datta V, Chaturvedi P. Congenital malformations in rural Maharashtra. Indian Pediatr. 2000;37:998–1001. - PubMed