Progressive airflow limitation is a feature of children with severe asthma
- PMID: 21211661
- PMCID: PMC3034305
- DOI: 10.1016/j.jaci.2010.10.036
Progressive airflow limitation is a feature of children with severe asthma
Abstract
Children with severe asthma have a premature loss of lung function during the adolescent years that is associated with increased symptom frequency and greater allergic sensitization during childhood.
Figures


References
-
- Wolfe R, Carlin JB, Oswald H, Olinsky A, Phelan PD, Robertson CF. Association between allergy and asthma from childhood to middle adulthood in an Australian cohort study. Am J Respir Crit Care Med. 2000;162:2177–81. - PubMed
-
- Rasmussen F, Taylor DR, Flannery EM, Cowan JO, Greene JM, Herbison GP, et al. Risk factors for airway remodeling in asthma manifested by a low postbronchodilator FEV1/vital capacity ratio: a longitudinal population study from childhood to adulthood. Am J Respir Crit Care Med. 2002;165:1480–8. - PubMed
-
- Sears MR, Greene JM, Willan AR, Wiecek EM, Taylor DR, Flannery EM, et al. A longitudinal, population-based, cohort study of childhood asthma followed to adulthood. N Engl J Med. 2003;349:1414–22. - PubMed