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. 2011 Jan;127(1):282-4.
doi: 10.1016/j.jaci.2010.10.036.

Progressive airflow limitation is a feature of children with severe asthma

Progressive airflow limitation is a feature of children with severe asthma

Anne M Fitzpatrick et al. J Allergy Clin Immunol. 2011 Jan.

Abstract

Children with severe asthma have a premature loss of lung function during the adolescent years that is associated with increased symptom frequency and greater allergic sensitization during childhood.

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Figures

Figure 1
Figure 1
Calculated change per year in baseline and post-bronchodilator FEV1 (shown in liters; A, B), FVC (shown in liters; B, C), and FEV1/FVC (shown as percent predicted; E, F). Lines represent the mean. MMA = mild-to-moderate asthma; SA = severe asthma. *p < 0.05; **p ≤ 0.01
Figure 2
Figure 2
Calculated yearly change in post-bronchodilator FEV1 percent predicted values in children with mild-to-moderate and severe asthma. Lines represent the mean. *p < 0.05

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