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Comment
. 2011 Jan 7;8(1):10-1.
doi: 10.1016/j.stem.2010.12.004.

Transition of endothelium to cartilage and bone

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Transition of endothelium to cartilage and bone

Ofer Shoshani et al. Cell Stem Cell. .
Free article

Abstract

Mesenchymal stromal cells (MSCs) are capable of differentiating into bone-forming osteoblasts. A recent Nature Medicine study (Medici et al., 2010) shows that the mislocalized bone in the human disease fibrodisplasia ossificans progressiva (FOP) originates from vascular endothelium that gives rise to MSCs.

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