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. 2011 Feb 9;133(5):1162-4.
doi: 10.1021/ja107849y. Epub 2011 Jan 7.

[3+2] cycloadditions of aryl cyclopropyl ketones by visible light photocatalysis

Zhan Lu  1 , Meihua Shen, Tehshik P Yoon
Affiliations

[3+2] cycloadditions of aryl cyclopropyl ketones by visible light photocatalysis

Zhan Lu et al. J Am Chem Soc. .

Abstract

We report a new method for the formal [3+2] reaction of aryl cyclopropyl ketones with olefins to generate highly substituted cyclopentane ring systems. The key initiation step in this process is the one-electron reduction of the ketone to the corresponding radical anion, which is accomplished using a photocatalytic system comprising Ru(bpy)(3)(2+), La(OTf)(3), and TMEDA.

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Figures

Scheme 1
Scheme 1
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