Mitochondrial stress signals revise an old aging theory
- PMID: 21215364
- DOI: 10.1016/j.cell.2010.12.023
Mitochondrial stress signals revise an old aging theory
Abstract
In this issue, Durieux et al. (2011) describe a tissue-specific signal, originating from mitochondria, that acts cell non-autonomously to regulate life span in the nematode, C. elegans. This new finding provides a first step toward resolving the relative contributions of mitochondrial free radical damage and signaling mechanisms in aging.
Copyright © 2011 Elsevier Inc. All rights reserved.
Comment on
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The cell-non-autonomous nature of electron transport chain-mediated longevity.Cell. 2011 Jan 7;144(1):79-91. doi: 10.1016/j.cell.2010.12.016. Cell. 2011. PMID: 21215371 Free PMC article.
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