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Review
. 1990 Jun;6(1-2):197-206.
doi: 10.1016/1011-1344(90)85090-j.

Photoreactions of furocoumarins with biomolecules

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Review

Photoreactions of furocoumarins with biomolecules

J Cadet et al. J Photochem Photobiol B. 1990 Jun.

Abstract

Recent aspects of the photoreactions of linear and angular furocoumarins with DNA and related compounds, including [2 + 2] cycloaddition to pyrimidine bases, covalent attachment to the osidic moiety of adenine nucleosides and photodynamic effects, are surveyed. Reactions of photoexcited furocoumarins with proteins and unsaturated lipids and the possible biological roles of the resulting adducts are also presented and discussed.

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