Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2011 Nov-Dec;26(6):347-67.
doi: 10.1177/0885066610393314. Epub 2011 Jan 10.

Pandemic influenza: implications for preparation and delivery of critical care services

Mary-Elise Manuell  1 , Mary Dawn T Co, Richard T Ellison 3rd
Affiliations

Pandemic influenza: implications for preparation and delivery of critical care services

Mary-Elise Manuell et al. J Intensive Care Med. 2011 Nov-Dec.

Abstract

In a 5-week span during the 1918 influenza A pandemic, more than 2000 patients were admitted to Cook County Hospital in Chicago, with a diagnosis of either influenza or pneumonia; 642 patients, approximately 31% of those admitted, died, with deaths occurring predominantly in patients of age 25 to 30 years. This review summarizes basic information on the biology, epidemiology, control, treatment and prevention of influenza overall, and then addresses the potential impact of pandemic influenza in an intensive care unit setting. Issues that require consideration include workforce staffing and safety, resource management, alternate sites of care surge of patients, altered standards of care, and crisis communication.

PubMed Disclaimer

References

    1. Nuzum JW, Pilot I, Stangl FH, Bonar BE. 1918 pandemic influenza and pneumonia in a large civil hospital. IMJ Ill Med J. 1976 Dec;150(6):612–616. - PubMed
    1. Neumann G, Noda T, Kawaoka Y. Emergence and pandemic potential of swine-origin H1N1 influenza virus. Nature. 2009 Jun 18;459(7249):931–939. - PMC - PubMed
    1. World Health Organization. [Accessed 4/13/10];Pandemic (H1N1) 2009. 2010 http://www.who.int/csr/don/2010_04_09/en/index.html. Update 95.
    1. Subbarao EK, London W, Murphy BR. A single amino acid in the PB2 gene of influenza A virus is a determinant of host range. J Virol. 1993 Apr;67(4):1761–1764. - PMC - PubMed
    1. Hatta M, Gao P, Halfmann P, Kawaoka Y. Molecular basis for high virulence of Hong Kong H5N1 influenza A viruses. Science. 2001 Sep 7;293(5536):1840–1842. - PubMed

Publication types

MeSH terms