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. 2011 Jan 10;16(1):466-76.
doi: 10.3390/molecules16010466.

Feeding deterrents against two grain storage insects from Euphorbia fischeriana

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Feeding deterrents against two grain storage insects from Euphorbia fischeriana

Zhu Feng Geng et al. Molecules. .

Abstract

The screening of several Chinese medicinal herbs for insecticidal principles showed that Euphorbia fischeriana roots possessed significant feeding deterrent activity against two stored-product insects (Tribolium castaneum and Sitophilus zeamais). From ethanol extract, four feeding deterrents were isolated by bioassay-guided fractionation. The compounds were identified as jolkinolide B, 12-deoxyphorbol 13-(9Z)-octadecenoate 20-acetate, 17-hydroxyjolkinolide A and B on the basis of their phytochemical and spectral data. Jolkinolide B and 17-hydroxyjolkinolide B possessed strong feeding deterrent activities against S. zeamais (EC₅₀ = 342.1 and 543.9 ppm, respectively) and T. castaneum adults (E₅₀ = 361.4 and 551.5 ppm, respectively). 17-Hydroxyjolkinolide A and 12-deoxyphorbol 13-(9Z)-octadecenoate 20-acetate A also exhibited feeding deterrent activity against the two grain storage insects with EC₅₀ values of 631.9 and 884.3 ppm for S. zeamais and 656.5 and 1058.4 ppm for T. castaneum adults.

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Figures

Figure 1
Figure 1
Structures of feeding deterrents isolated from Euphorbia fischeriana roots.

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