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. 1987 Nov;2(11):328-32.
doi: 10.1016/0169-5347(87)90108-X.

Molecular evolution of ubiquitin genes

P M Sharp  1 , W H Li
Affiliations

Molecular evolution of ubiquitin genes

P M Sharp et al. Trends Ecol Evol. 1987 Nov.

Abstract

Ubiquitin is a singular protein with multiple functions. It is probably the most slowly evolving protein known, is encoded by genes with a unique structure, and provides an intriguing case study for various aspects of molecular evolution. In particular, the multiple ubiquitin-coding repeats which have been characterized in man, yeast and a slime mould graphically illustrate the dynamics of concerted evolution, but cast doubts on the effectiveness of this process for unlinked arrays in this repeat family.

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