Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2011 Mar;7(3):714-7.
doi: 10.1039/c0mb00217h. Epub 2011 Jan 14.

The de novo engineering of pyrrolysyl-tRNA synthetase for genetic incorporation of L-phenylalanine and its derivatives

Yane-Shih Wang  1 , William K Russell, Zhiyong Wang, Wei Wan, Lindsey E Dodd, Pei-Jing Pai, David H Russell, Wenshe R Liu
Affiliations

The de novo engineering of pyrrolysyl-tRNA synthetase for genetic incorporation of L-phenylalanine and its derivatives

Yane-Shih Wang et al. Mol Biosyst. 2011 Mar.

Abstract

Using evolved pyrrolysyl-tRNA synthetase-tRNA(CUA)(Pyl) pairs, L-phenylalanine, p-iodo-L-phenylalanine and p-bromo-L-phenylalanine have been genetically incorporated into proteins at amber mutation sites in E. coli.

PubMed Disclaimer

Publication types

MeSH terms

LinkOut - more resources