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. 2011 Mar 4;13(5):828-31.
doi: 10.1021/ol102987n. Epub 2011 Jan 14.

Organocatalytic enantioselective Friedel-crafts reactions of 1-naphthols with aldimines

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Organocatalytic enantioselective Friedel-crafts reactions of 1-naphthols with aldimines

Guixia Liu et al. Org Lett. .

Abstract

An organocatalytic enantioselective Friedel-Crafts reaction of 1-naphthols with aldimines has been developed. The method affords a direct access to chiral aminoarylnaphthols in good yields and with good to high enantioselectivities.

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