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Review
. 2011 Feb;52(2):129-39.
doi: 10.1097/MPG.0b013e3181ffde67.

Esophageal impedance monitoring for gastroesophageal reflux

Hayat M Mousa  1 , Rachel Rosen, Frederick W Woodley, Marina Orsi, Daneila Armas, Christophe Faure, John Fortunato, Judith O'connor, Beth Skaggs, Samuel Nurko
Affiliations
Review

Esophageal impedance monitoring for gastroesophageal reflux

Hayat M Mousa et al. J Pediatr Gastroenterol Nutr. 2011 Feb.

Abstract

Dual pH-multichannel intraluminal impedance (pH-MII) is a sensitive tool for evaluating overall gastroesophageal reflux disease, and particularly for permitting detection of nonacid reflux events. pH-MII technology is especially useful in the postprandial period or at other times when gastric contents are nonacidic.pH-MII was recently recognized by the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition as being superior to pH monitoring alone for evaluation of the temporal relation between symptoms and gastroesophageal reflux. In children, pH-MII is useful to correlate symptoms with reflux (particularly nonacid reflux), to quantify reflux during tube feedings and the postprandial period, and to assess efficacy of antireflux therapy. This clinical review is simply an evidence-based overview addressing the indications, limitations, and recommended protocol for the clinical use of pH-MII in children.

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Figures

FIGURE 1
FIGURE 1
Nonacid gastroesophageal reflux event.
FIGURE 2
FIGURE 2
Acid gastroesophageal reflux event.
FIGURE 3
FIGURE 3
Regression analysis plot. The temporal relation between the frequency and duration of gastroesophageal reflux (GER) and coughing episodes. Blue and red wave forms represent nonacid and acid gastroesophageal reflux episodes, respectively. Green wave forms represent coughing episodes.
See this image and copyright information in PMC

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