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Review
. 2011 Feb;11(4):657-74.
doi: 10.1002/pmic.201000412. Epub 2011 Jan 17.

Energy matters: mitochondrial proteomics for biomedicine

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Review

Energy matters: mitochondrial proteomics for biomedicine

Elisabetta Gianazza et al. Proteomics. 2011 Feb.

Abstract

This review compiles results of medical relevance from mitochondrial proteomics, grouped either according to the type of disease - genetic or degenerative - or to the involved mechanism - oxidative stress or apoptosis. The findings are commented in the light of our current understanding of uniformity/variability in cell responses to different stimuli. Specificities in the conceptual and technical approaches to human mitochondrial proteomics are also outlined.

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