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. 2010 Mar 23;7622(76225I):76225I (2010).
doi: 10.1117/12.844909.

Progress in the Development of a new Angiography Suite including the High Resolution Micro-Angiographic Fluoroscope (MAF), a Control, Acquisition, Processing, and Image Display System (CAPIDS), and a New Detector Changer Integrated into a Commercial C-Arm Angiography Unit to Enable Clinical Use

Weiyuan Wang  1 , Ciprian N Ionita, Christos Keleshis, Andrew Kuhls-Gilcrist, Amit Jain, Daniel Bednarek, Stephen Rudin
Affiliations

Progress in the Development of a new Angiography Suite including the High Resolution Micro-Angiographic Fluoroscope (MAF), a Control, Acquisition, Processing, and Image Display System (CAPIDS), and a New Detector Changer Integrated into a Commercial C-Arm Angiography Unit to Enable Clinical Use

Weiyuan Wang et al. Proc SPIE Int Soc Opt Eng. .

Abstract

Due to the high-resolution needs of angiographic and interventional vascular imaging, a Micro-Angiographic Fluoroscope (MAF) detector with a Control, Acquisition, Processing, and Image Display System (CAPIDS) was installed on a detector changer which was attached to the C-arm of a clinical angiographic unit. The MAF detector provides high-resolution, high-sensitivity, and real-time imaging capabilities and consists of a 300 μm-thick CsI phosphor, a dual stage micro-channel plate light image intensifier (LII) coupled to a fiber optic taper (FOT), and a scientific grade frame-transfer CCD camera, providing an image matrix of 1024×1024 35 μm square pixels with 12 bit depth. The Solid-State X-Ray Image Intensifier (SSXII) is an EMCCD (Electron Multiplying charge-coupled device) based detector which provides an image matrix of 1k×1k 32 μm square pixels with 12 bit depth. The changer allows the MAF or a SSXII region-of-interest (ROI) detector to be inserted in front of the standard flat-panel detector (FPD) when higher resolution is needed during angiographic or interventional vascular imaging procedures. The CAPIDS was developed and implemented using LabVIEW software and provides a user-friendly interface that enables control of several clinical radiographic imaging modes of the MAF or SSXII including: fluoroscopy, roadmapping, radiography, and digital-subtraction-angiography (DSA). The total system has been used for image guidance during endovascular image-guided interventions (EIGI) using prototype self-expanding asymmetric vascular stents (SAVS) in over 10 rabbit aneurysm creation and treatment experiments which have demonstrated the system's potential benefits for future clinical use.

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Figures

Figure 1
Figure 1
MAF Detector.
Figure 2
Figure 2
The new Angiography Suite with the MAF Detector deployed using the new detector changer.
Figure 3
Figure 3
CAPIDS Control Panel - Acquisition (upper), zoomed right side of the panel (lower).
Figure 4
Figure 4
CAPIDS Control Panel - Playback (upper), zoomed right side of the panel (lower).
Figure 5
Figure 5
Main components of the detector changer.
Figure 6
Figure 6
Detector changer position switch.
Figure 7
Figure 7
Detector changer latch and bolt.
Figure 8
Figure 8
MAF in retracted position (left) and inserted position (right).
Figure 9
Figure 9
EIGI SAVS.
Figure 10
Figure 10
SAVS.
Figure 11
Figure 11
Stent deployment misalignment.
Figure 12
Figure 12
Thrombosed aneurysm for rabbit case#2:3D microCT reconstruction (left), and single projection image (right) of resected vessel.
Figure 13
Figure 13
Comparison between FPD and MAF.
See this image and copyright information in PMC

References

    1. Ionita CN, et al. Implementation of a high-sensitivity Micro-Angiographic Fluoroscope (HS-MAF) for in-vivo endovascular image guided interventions (EIGI) and region-of-interest computed tomography (ROI-CT) Proc Soc Photo Opt Instrum Eng. 2008. p. 69181I. [PMCID:2572822] http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dop.... - PMC - PubMed
    1. Patel V, et al. Effect of projection angles used in multi-view reconstruction (MVR) using images from a microangiographic (MA) detector and an image-intensifier (II) system. Medical Physics. 2006;33(6):2229–2229.
    1. Keleshis C. AUTOMATED HIGH RESOLUTION, MICRO-ANGIOGRAPHIC FLUOROSCOPY MEDICAL SYSTEMS. 2009. http://hdl.handle.net/10465/449.
    1. Kuhls-Gilcrist A, et al. The Solid-State X-Ray Image Intensifier (SSXII): An EMCCD-Based X-Ray Detector. Proc Soc Photo Opt Instrum Eng. 2008. p. nihpa68284. [PMCID:2557100] http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dop.... - PMC - PubMed
    1. Yadava GK, et al. Generalized Objective Performance Assessment of a New High-Sensitivity Microangiographic Fluoroscopic (HSMAF) Imaging System. Proc Soc Photo Opt Instrum Eng. 2008. p. nihpa68288. [PMCID:2557068] http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dop.... - PMC - PubMed

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