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. 2011 Mar;67(3):215-24.
doi: 10.1007/s00228-010-0981-4. Epub 2011 Jan 18.

Suspected adverse reactions associated with herbal products used for weight loss: a case series reported to the Italian National Institute of Health

Annabella Vitalone  1 , Francesca Menniti-Ippolito, Paola Angela Moro, Fabio Firenzuoli, Roberto Raschetti, Gabriela Mazzanti
Affiliations

Suspected adverse reactions associated with herbal products used for weight loss: a case series reported to the Italian National Institute of Health

Annabella Vitalone et al. Eur J Clin Pharmacol. 2011 Mar.

Abstract

Purpose: The aim of this study was to describe suspected adverse reactions (ARs) associated with herbal products used for weight control in Italy.

Methods: Spontaneous reports of suspected ARs associated with herbal products used for weight control were collected by the Italian National Institute of Health (April 2002 to June 2010), and the causality assessment was performed.

Results: Forty-six of the suspected ARs were associated with herbal products used for weight control. Women were involved in 85% of the reports. The reactions affected mainly the cardiovascular system, the skin, the digestive system, the central nervous system, and the liver. A large proportion of ARs were serious. In more than half of the suspected ARs, the use of other therapies (herbs and/or drugs) was reported, while concomitant conditions were present in 22% of the reports.

Conclusions: The use of herbal dietary supplements for weight loss is associated with several ARs. Considering the risk/benefit ratio, consumers should pay attention when using these products.

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