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Review
. 2011 Mar;43(2):133-41.
doi: 10.3109/07853890.2010.549148. Epub 2011 Jan 18.

Golimumab - a new tool in the armoury against inflammatory arthritis

Zoe Ash  1 , Paul Emery
Affiliations
Review

Golimumab - a new tool in the armoury against inflammatory arthritis

Zoe Ash et al. Ann Med. 2011 Mar.

Abstract

The development of biological drugs blocking tumour necrosis factor-alpha (TNF-α) has had a dramatic impact on the treatment of inflammatory arthritis in recent years. Golimumab is a fully human monoclonal antibody which inhibits TNF-α. It is licensed for the treatment of rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis. In this review we evaluate the results of phase III studies using golimumab and explore the place of golimumab in the treatment of these diseases.

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