Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Multicenter Study
. 2011 Mar;204(3):209.e1-7.
doi: 10.1016/j.ajog.2010.10.897. Epub 2011 Jan 17.

Evaluation of a screening tool for bleeding disorders in a US multisite cohort of women with menorrhagia

Claire S Philipp  1 , Ambarina Faiz, John A Heit, Peter A Kouides, Andrea Lukes, Sidney F Stein, Vanessa Byams, Connie H Miller, Roshni Kulkarni
Affiliations
Multicenter Study

Evaluation of a screening tool for bleeding disorders in a US multisite cohort of women with menorrhagia

Claire S Philipp et al. Am J Obstet Gynecol. 2011 Mar.

Abstract

Objective: The purpose of this study was to determine the usefulness of a simple screening tool for bleeding disorders in a multisite population of women with menorrhagia.

Study design: Women with menorrhagia between the ages of 18 and 50 years from 6 geographically diverse US centers underwent hemostatic testing for bleeding disorders, complete blood cell count, and ferritin. A questionnaire that contained all elements of the 8-question screening tool was administered. Sensitivity of the screening tool, a screening tool with a pictorial blood assessment chart (PBAC) score of >185, and a screening tool with serum ferritin were calculated for hemostatic disorders.

Results: Two hundred and seventeen women who were identified with a PBAC score of ≥100 participated in the study. The sensitivity of the screening tool was 89% for hemostatic defects, and sensitivity increased to 93% and 95% with a serum ferritin level of ≤20 ng/mL and a PBAC score of >185, respectively.

Conclusion: This study confirms the usefulness of a short screening tool for the stratification of women with menorrhagia for hemostatic evaluation.

PubMed Disclaimer

Comment in

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Dilley A, Drews C, Miller C, et al. Von Wille-brand Disease and other inherited bleeding disorders in women with diagnosed menorrhagia. Obstet Gynecol. 2001;97:630–6. - PubMed
    1. Rees M. Menorrhagia. BMJ (Clin Res Ed) 1987;294:759–62. - PMC - PubMed
    1. Kadir RA, Economides DL, Sabin CA, Owens D, Lee CA. Frequency of inherited bleeding disorders in women with menorrhagia. Lancet. 1998;351:485–9. - PubMed
    1. Edlund M, Blomback M, von Schoultz B, Andersson O. On the value of menorrhagia as a predictor for coagulation disorders. Am J Hematol. 1996;53:234–8. - PubMed
    1. Philipp CS, Dilley A, Miller CH, et al. Platelet functional defects in women with unexplained menorrhagia. J Thromb Haemost. 2003;1:477–84. - PubMed

Publication types