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Review

Platelets

Patrick J. Stiff
H Kenneth Walker  1 , W Dallas Hall  1 , J Willis Hurst  1
, editors.
In: Clinical Methods: The History, Physical, and Laboratory Examinations. 3rd edition. Boston: Butterworths; 1990. Chapter 154.
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Review

Platelets

Patrick J. Stiff.
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Excerpt

The platelet is a circulating anuclear fragment of a bone marrow megakaryocyte, 3 to 4 μm in diameter, with limited synthetic capability. The mean normal platelet count is between 250,000 and 260,000 cells/mm3, although there is a wide range of accepted normal values in most laboratories that extend as low as 150,000 to as high as 400,000/mm3.

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References

    1. Dumoulin-Lagrange M, Capelle C. Evaluation of automated platelet counters for the enumeration and sizing of platelets in the diagnosis and management of hemostatic problems. Semin Throm Hemos. 1983;9:235–44. - PubMed
    1. Eisenstaedt R. Blood component therapy in the treatment of platelet disorders. Semin Hematol. 1986;23:2–7. - PubMed
    1. Gewirtz AM. Human megakaryocutopoiesis. Semin Hematol. 1986;23:27–42. - PubMed
    1. Holmsen H. Platelet metabolism and activation. Semin Hematol. 1985;22:219–40. - PubMed
    1. Karpatkin S. Autoimmune thrombocytopenic purpura. Semin Hematol. 1985;22:260–88. - PubMed

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