Embryonal rhabdomyosarcoma of the cervix and appendiceal carcinoid tumor
- PMID: 21252797
- DOI: 10.1097/AOG.0b013e3182051dd0
Embryonal rhabdomyosarcoma of the cervix and appendiceal carcinoid tumor
Abstract
Background: Rhabdomyosarcomas, particularly those of gynecologic origin, are very rare in adults. As a result, there is little literature on the optimal staging procedure and treatment modalities for this population.
Case: A 43-year-old woman presented with a long-standing history of menorrhagia and was subsequently diagnosed with embryonal rhabdomyosarcoma of the cervix. She underwent a total abdominal hysterectomy, bilateral salpingo-oophorectomy, lymph node dissection, omentectomy, and appendectomy, which also revealed a synchronous tubular carcinoid tumor of appendiceal origin. Plans for treatment involve adjuvant chemotherapy with vincristine, dactinomycin, and cyclophosphamide.
Conclusion: This case adds to the small body of literature surrounding cervical embryonal rhabdomyosarcoma in women over the age of 40 years and proposes that appendectomy be considered during surgical management.
References
-
- Ferguson SE, Gerald W, Barakat R, Chi DS, Soslow RA. Clinicopathologic features of rhabdomyosarcoma of gynecologic origin in adults. Am J Surg Pathol 2007;31:382–9.
-
- Crist WM, Anderson JR, Meza JL, Fryer C, Raney RB, Ruymann FB, et al. Intergroup rhabdomyosarcoma study-IV: results for patients with nonmetastatic disease. J Clin Oncol 2001;19:3091–102.
-
- Miyamoto T, Shiozawa T, Nakamura T, Konishi I. Sarcoma botryoides of the uterine cervix in a 46-year-old woman: case report and literature review. Int J Gynecol Pathol 2004;23:78–82.
-
- Kaushal A, Patel A, Shah S, Patel KM, Trivedi P. Rhabdomyosarcoma of the uterine cervix in a 44 year female: a rare presentation. Indian J Med Paediatr Oncol 2006;27:35–7.
-
- Koukourakis GV, Kouloulias V, Zacharias G, Maravelis G, Papadimitriou C, Platoni K, et al. Embryonal rhabdomyosarcoma of the uterine cervix. Clin Transl Oncol 2009;11:399–402.
