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Review
. 2011 Jul;64(1):1-3.
doi: 10.1016/j.phrs.2011.01.007. Epub 2011 Jan 19.

Antiretroviral drugs in HIV-infected children

Alessandra Viganò, Valeria Manfredini, Francesca Penagini, Vania Giacomet, Gian Vincenzo Zuccotti
Review

Antiretroviral drugs in HIV-infected children

Alessandra Viganò et al. Pharmacol Res. 2011 Jul.

Abstract

Availability of highly active antiretroviral therapy has dramatically increased survival rates and substantially modified the course of HIV infection, which has now become a chronic disease both in adults and in children. Treatment strategies in paediatric patients have to face with specific challenges associated with selection of a successful antiretroviral drug regimen, long-lasting maintenance of adherence to therapy, short and long-term drug-related toxicities and emerging of extensive drug resistance. This review shows an up-to-date picture of the ultimate advances of antiretroviral therapy in HIV-infected children.

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