Regulator of Ras depalmitoylation and retrograde trafficking: a new hat for FKBP
- PMID: 21255722
- DOI: 10.1016/j.molcel.2011.01.009
Regulator of Ras depalmitoylation and retrograde trafficking: a new hat for FKBP
Abstract
In this issue of Molecular Cell, Ahearn et al. (2011) identified FKBP12 as a novel regulator of Ras signaling through its modulation of depalmitoylation of H-Ras and its recycling from plasma membrane to the Golgi.
Copyright © 2011 Elsevier Inc. All rights reserved.
Comment on
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FKBP12 binds to acylated H-ras and promotes depalmitoylation.Mol Cell. 2011 Jan 21;41(2):173-85. doi: 10.1016/j.molcel.2011.01.001. Mol Cell. 2011. PMID: 21255728 Free PMC article.
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