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. 2011 Mar;204(3):261.e1-261.e10.
doi: 10.1016/j.ajog.2010.11.040. Epub 2011 Jan 21.

Aberrant fetal growth and early, late, and postneonatal mortality: an analysis of Milwaukee births, 1996-2007

Han-Yang Chen  1 , Suneet P Chauhan, Trina C Salm Ward, Naoyo Mori, Eric T Gass, Ron A Cisler
Affiliations

Aberrant fetal growth and early, late, and postneonatal mortality: an analysis of Milwaukee births, 1996-2007

Han-Yang Chen et al. Am J Obstet Gynecol. 2011 Mar.

Abstract

Objective: The objective of the study was to ascertain the association between fetal growth (small- [SGA], appropriate- [AGA], and large-for-gestational-age [LGA]) and early, late, and postneonatal mortality.

Study design: Birth certificate data for nonanomalous singletons, delivered from 1996 to 2007, were obtained for Milwaukee residents. Multivariate logistic regression analyses, adjusted for 19 covariates, determined the association between fetal growth and mortality.

Results: Among the 123,383 live births, SGA was 57% higher than LGA (11% vs 7%). The infant mortality rate for SGA was 11.0, AGA, 5.3, and LGA, 2.7/1000 live births. SGA was a significant risk factor for early (adjusted odds ratio, 2.66) and late (2.06) but not postneonatal mortality. The adjusted risk of mortality for LGA was not significantly different from AGA. Over 12 years, 3 types of mortality for aberrant fetal growth did not change significantly.

Conclusion: In the city of Milwaukee, aberrant fetal growth was variably associated with early, late, and postneonatal mortality.

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