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Editorial
. 2011 Jan;34(1):10-1.
doi: 10.1002/clc.20867.

The slow cardiac myosin regulatory light chain in heart failure

Daniel F Pauly
Editorial

The slow cardiac myosin regulatory light chain in heart failure

Daniel F Pauly. Clin Cardiol. 2011 Jan.
No abstract available

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Figures

Figure 1
Figure 1
Schematic diagram of the myosin molecule. The head region contains the actin binding regions and the ATP binding sites. The hinge region is stabilized by essential light chain proteins and regulatory light chain proteins. The myosin rod region then extends outward. Abbreviations: ATP, adenosine triphosphate.
See this image and copyright information in PMC

Comment in

References

    1. Palmer BM. Thick filament proteins and performance in human heart failure. Heart Fail Rev. 2005;10:187–197. - PubMed
    1. Li Y, Gang W, Qizhu T, et al. Slow cardiac myosin regulatory light chain 2 (myl2) was down‐expressed in chronic heart failure patients. Clin Cardiol. 2010;33:30–34. - PMC - PubMed
    1. Ding P, Huang J, Battiprolu PK, et al. Cardiac myosin light chain kinase is necessary for myosin regulatory light chain phosphorylation and cardiac performance in vivo. J Biol Chem. 2010. doi:10.1074/jbc.M110.160499. - PMC - PubMed
    1. Min KD, Asakura M, Liao Y, et al. Identification of genes related to heart failure using global gene expression profiling of human failing myocardium. Biochem Biophys Res Commun. 2010;393:55–60. - PubMed

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