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Randomized Controlled Trial
. 2011 Feb;127(2):261-8.
doi: 10.1542/peds.2010-2334. Epub 2011 Jan 24.

Early experiences and predictors of recruitment success for the National Children's Study

Leonardo Trasande  1 , Howard F Andrews, Christopher Goranson, Wenhui Li, Elise C Barrow, Suzette B Vanderbeek, Brittany McCrary, Suzannah B Allen, Kathleen D Gallagher, Andrew Rundle, James Quinn, Barbara Brenner
Affiliations
Randomized Controlled Trial

Early experiences and predictors of recruitment success for the National Children's Study

Leonardo Trasande et al. Pediatrics. 2011 Feb.

Abstract

Objectives: We aimed to describe 17 months of experience with household recruitment of live births for the National Children's Study in Queens, a highly urban, diverse borough of New York City (NYC), and to assess predictors of recruitment success.

Methods: Recruitment data (enumeration, pregnancy screening of age-eligible women, identification of pregnancies, and consent) for the period of January 2009 through May 2010 were calculated. Geographic information systems were used to create 11 community-level variables for each of the 18 study segments where recruitment occurred, using US Census, NYC Office of Vital Statistics, NYC Department of City Planning, and NYC Police Department data. Recruitment yields were analyzed with respect to these variables at the segment level.

Results: Enumeration identified 4889 eligible women, of whom 4333 (88.6%) completed the pregnancy screener. At least 115 births were lost because of an inability of the pregnancy screener to identify pregnant women, whereas another 115 could be expected to be lost because of missed enumerations and pregnancy screeners. The consent rate was 60.3%. Segments with higher percentages of low birth weight had higher enumeration, pregnancy screening, and consent rates.

Conclusions: In a highly immigrant, urban setting, households could be approached for recruitment of women to participate in the National Children's Study with consent rates equal to those experienced in clinical settings. Refinement of the pregnancy screener and other recruitment materials presents an opportunity to optimize recruitment, improve the representativeness of study participants, and improve the cost-effectiveness of study execution.

Trial registration: ClinicalTrials.gov NCT00852904.

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Figures

FIGURE 1
FIGURE 1
Consent outcomes in the NCS in Queens, New York, for January 2009 through May 2010.
FIGURE 2
FIGURE 2
Scheme for introductory questions in the pregnancy screener for National Children's Study original Vanguard Study centers.
See this image and copyright information in PMC

References

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