Efficacy of quantified home-based exercise and supervised exercise in patients with intermittent claudication: a randomized controlled trial
- PMID: 21262997
- PMCID: PMC3154843
- DOI: 10.1161/CIRCULATIONAHA.110.963066
Efficacy of quantified home-based exercise and supervised exercise in patients with intermittent claudication: a randomized controlled trial
Abstract
Background: This prospective, randomized, controlled clinical trial compared changes in exercise performance and daily ambulatory activity in peripheral artery disease patients with intermittent claudication after a home-based exercise program, a supervised exercise program, and usual-care control.
Methods and results: Of the 119 patients randomized, 29 completed home-based exercise, 33 completed supervised exercise, and 30 completed usual-care control. Both exercise programs consisted of intermittent walking to nearly maximal claudication pain for 12 weeks. Patients wore a step activity monitor during each exercise session. Primary outcome measures included claudication onset time and peak walking time obtained from a treadmill exercise test; secondary outcome measures included daily ambulatory cadences measured during a 7-day monitoring period. Adherence to home-based and supervised exercise was similar (P=0.712) and exceeded 80%. Both exercise programs increased claudication onset time (P<0.001) and peak walking time (P<0.01), whereas only home-based exercise increased daily average cadence (P<0.01). No changes were seen in the control group (P>0.05). The changes in claudication onset time and peak walking time were similar between the 2 exercise groups (P>0.05), whereas the change in daily average cadence was greater with home-based exercise (P<0.05).
Conclusions: A home-based exercise program, quantified with a step activity monitor, has high adherence and is efficacious in improving claudication measures similar to a standard supervised exercise program. Furthermore, home-based exercise appears more efficacious in increasing daily ambulatory activity in the community setting than supervised exercise.
Trial registration: ClinicalTrials.gov NCT00618670.
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Comment in
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Review of an article: Gardner AW, Parker DE, Montgomery PS, Scott KJ, Blevins SM. Efficacy of quantified home-based exercise and supervised exercise in patients with intermittent claudication: a randomized controlled trial. Circulation 2011;123(5):491-98.J Vasc Nurs. 2011 Sep;29(3):126-7. doi: 10.1016/j.jvn.2011.07.002. J Vasc Nurs. 2011. PMID: 21867905 No abstract available.
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