Review
doi: 10.1016/0167-5699(90)90173-7.
Biological and clinical aspects of interleukin 6
Affiliations
- PMID: 2127356
- DOI: 10.1016/0167-5699(90)90173-7
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Review
Biological and clinical aspects of interleukin 6
Immunol Today.
1990 Dec.
Abstract
Interleukin 6 (IL-6) is a multi-functional cytokine that is produced by a range of cells and plays a central role in host defense mechanisms. Abnormal production of IL-6 has been suggested to be involved in glomerulonephritis, plasmacytomagenesis and in the pathogenesis of autoimmune diseases. In this review, Toshio Hirano and colleagues discuss the possible involvement of IL-6 in a variety of diseases, the regulatory mechanism(s) of expression of the IL-6 gene and the structure and function of the IL-6 receptor.
Comment in
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Further functions of IL-6.Immunol Today. 1991 May;12(5):170. doi: 10.1016/S0167-5699(05)80050-7. Immunol Today. 1991. PMID: 1750926 No abstract available.
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