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Clinical Trial
. 1990 Dec;9(6):584-7.

Phase II evaluation of recombinant gamma-interferon in patients with advanced pancreatic carcinoma: a Southwest Oncology Group study

D D Von Hoff  1 , T R Fleming, J S Macdonald, P J Goodman, J Van Damme, T D Brown, T O'Rourke, L G Feun, M D Keppen
Affiliations
  • PMID: 2127424
Clinical Trial

Phase II evaluation of recombinant gamma-interferon in patients with advanced pancreatic carcinoma: a Southwest Oncology Group study

D D Von Hoff et al. J Biol Response Mod. 1990 Dec.

Abstract

Thirty evaluable patients with advanced carcinoma of the pancreas received treatment with either daily x 5 bolus or continuous infusion x 5 days recombinant gamma-interferon. No responses were noted. Major toxicities included fever, hypotension, and flu-like symptoms. gamma-Interferon does not appear to be an active single agent for patients with advanced pancreatic cancer.

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