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Review
. 2011 May;25(4):561-8.
doi: 10.1016/j.avsg.2010.11.007. Epub 2011 Jan 28.

Current usage and future directions for the bovine pericardial patch

Xin Li  1 , Yuanyuan Guo, Kenneth R Ziegler, Lynn S Model, Sammy D D Eghbalieh, Robert A Brenes, Susun T Kim, Chang Shu, Alan Dardik
Affiliations
Review

Current usage and future directions for the bovine pericardial patch

Xin Li et al. Ann Vasc Surg. 2011 May.

Abstract

Bovine pericardium (BP) is widely used in surgery and is commonly used as a patch after arteriotomy in cardiovascular surgery. BP patches have several advantages compared with prosthetic patches, including superior biocompatability, easy handling, less suture line bleeding, and possibly reduced rates of infection. These advantages of BP have led to its common use during carotid endarterectomy (CEA). However, long-term clinical results reported after CEA have suggested several issues that may be related to the patch, including restenosis, pseudoaneurysm formation, infection, fibrosis, calcification, and thrombosis. These complications may diminish the long-term efficacy of CEA and suggest potential areas for improvement of surgical patches. Understanding the mechanisms by which BP heals after patch angioplasty may lead to next generation tissue-engineered patches.

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Figures

Figure 1
Figure 1
Bovine pericardial patch, stained with H&E. Light red staining is indicative of collagen. There are no cells visible within the patch.
Figure 2
Figure 2
Bovine pericardial patch, stained for elastin. No elastin is seen. Dark red staining is indicative of collagen.
Figure 3
Figure 3
Bovine pericardial patch, stained with Trichome staining. Dark blue staining is indicative of collagen.
See this image and copyright information in PMC

References

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